http://pubs.acs.org/doi/10.1021/acs.organomet.5b00727
Substituent Effect on the Catalytic Activity of Ruthenium(II) Complexes Bearing a Pyridyl-Supported Pyrazolyl-Imidazolyl Ligand for Transfer Hydrogenation of Ketones
Huining Chai†, Tingting Liu†, Qingfu Wang†, and Zhengkun Yu*†‡
† Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian, Liaoning 116023, People’s Republic of China
‡ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, People’s Republic of China
Organometallics, Article ASAP
DOI: 10.1021/acs.organomet.5b00727
Publication Date (Web): October 20, 2015
Air- and moisture-stable ruthenium(II) complexes bearing a multisubstituted pyrazolyl-imidazolyl-pyridine ligand were synthesized and structurally characterized by NMR and X-ray single-crystal crystallographic analyses. The substituents on the imidazolyl moiety of the NNN ligand exhibited a remarkable impact on the catalytic activity of the corresponding Ru(II) complexes for transfer hydrogenation of ketones in refluxing 2-propanol, following the order NHTs > Me > H > NO2, to tune the catalytic activity. The highest final TOF value of 345 600 h–1was reached by means of 0.05 mol % of the Ru(II)-NHTs-substituted NNN complex as the catalyst. The corresponding structurally confirmed RuH complexes are proposed as the catalytically active species.
