Removing Homogeneous Catalysts from Reaction Mixtures for Product Isolation

Metathesis Catalyst Removal Techniques

 http://allthingsmetathesis.com/metathesis-catalyst-removal-techniques/

While this is directed towards removal of Metathesis Catalysts. The techniques and tips, I believe, could have application with a variety of homogeneous catalysts.

Abstract:

Purification of a metathesis mixture can give you all sorts of problems (especially when using high catalyst loadings). Sometimes you need multiple columns to get a colorless product. Sometimes residual ruthenium can cause the product to isomerize during distillation or decompose over time. Numerous methods have been reported for the removal of metathesis catalysts after a reaction. In general, you need a ligand or adsorbent that binds ruthenium better than your product, or a reagent that will react with the residual ruthenium preferentially. Unfortunately the optimal process tends to vary on a case by case basis.